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NEET Biology: Human Physiology Practice Questions

15 free multiple-choice questions on Human Physiology for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. Which muscle plays the most crucial role in the process of breathing (ventilation)?

    • AScalenes
    • BAbdominal muscles
    • CDiaphragm
    • DIntercostal muscles
    Show answer & explanation

    Correct answer: C — Diaphragm

    The diaphragm is the primary muscle responsible for inhalation, as its contraction causes it to move downward, increasing the volume of the thoracic cavity.

  2. Q2. Which component of blood is primarily responsible for transporting the majority of oxygen from the lungs to the rest of the body?

    • AWhite blood cells
    • BRed blood cells
    • CPlatelets
    • DPlasma
    Show answer & explanation

    Correct answer: B — Red blood cells

    Red blood cells contain hemoglobin, which binds reversibly with oxygen, thus facilitating its transport throughout the circulatory system.

  3. Q3. Hemoglobin in red blood cells is primarily responsible for the transport of which gas in the circulatory system?

    • ANitrogen
    • BHydrogen
    • CCarbon Dioxide
    • DOxygen
    Show answer & explanation

    Correct answer: D — Oxygen

    Hemoglobin contains iron, which binds reversibly with oxygen, allowing it to be effectively transported from the lungs to the rest of the body tissues.

  4. Q4. Which of the following is a chronic respiratory condition resulting from prolonged exposure to irritating dusts and fumes in an industrial setting?

    • AChronic Obstructive Pulmonary Disease (COPD)
    • BTuberculosis
    • CAsthma
    • DPulmonary Embolism
    Show answer & explanation

    Correct answer: A — Chronic Obstructive Pulmonary Disease (COPD)

    Chronic exposure to industrial pollutants leads to chronic lung diseases like COPD, which involves persistent inflammation and airflow limitation.

  5. Q5. Hypertension is generally classified based on the cause. Which type of hypertension is most commonly associated with kidney disease and hormonal imbalances?

    • AArterial Hypertension
    • BSecondary Hypertension
    • CBenign Hypertension
    • DEssential (Primary) Hypertension
    Show answer & explanation

    Correct answer: B — Secondary Hypertension

    Secondary hypertension refers to high blood pressure caused by an underlying medical condition, such as kidney disease, endocrine disorders, or thyroid issues. This contrasts with essential (primary) hypertension, which is the most common form.

  6. Q6. During stable angina, the chest pain is primarily caused by the imbalance between myocardial oxygen supply and demand during physical exertion. What is the main underlying structural issue causing this limitation?

    • ASudden blockage of the coronary arteries
    • BIncreased heart rate leading to systemic hypoxia
    • CAcute rupture of a thrombus
    • DFixed narrowing of coronary arteries due to atherosclerosis
    Show answer & explanation

    Correct answer: D — Fixed narrowing of coronary arteries due to atherosclerosis

    Stable angina occurs when the fixed narrowing of the coronary arteries (atherosclerosis) limits blood flow during increased myocardial oxygen demand (like during exercise).

  7. Q7. What is the interval that measures the time taken for the electrical impulse to travel from the atria to the ventricles?

    • APR interval
    • BST segment
    • CQT interval
    • DRR interval
    Show answer & explanation

    Correct answer: A — PR interval

    The PR interval measures the time delay between the start of atrial depolarization (P wave) and the start of ventricular depolarization (QRS complex).

  8. Q8. The accumulation of inflammatory cells (like eosinophils and mast cells) in the bronchial walls is characteristic of which stage of the asthma disease process?

    • AAcute phase
    • BEarly sensitization
    • CLate chronic phase
    • DReversal phase
    Show answer & explanation

    Correct answer: C — Late chronic phase

    Chronic inflammation and cellular infiltration characterize the chronic phase of asthma, leading to persistent airway remodeling.

  9. Q9. Which valve is responsible for preventing the backflow of blood from the left ventricle into the left atrium during ventricular systole?

    • AMitral valve
    • BPulmonary valve
    • CAortic valve
    • DTricuspid valve
    Show answer & explanation

    Correct answer: A — Mitral valve

    The aortic valve controls flow from the left ventricle to the aorta, and the mitral valve controls flow between the left atrium and left ventricle. During ventricular systole, the mitral valve closes to prevent backflow into the atrium, while the aortic valve opens to allow ejection into the aorta. The question refers to the valve preventing backflow into the atrium, which is the mitral valve (incorrectly phrased in options, needs re-evaluation of flow path). Corrected context: The valve preventing backflow from ventricle to atrium during systole is the Mitral valve. Let's rephrase to ensure clarity on the specific valve action related to backflow.

  10. Q10. Which of the following is a major macromolecule dissolved in the lymph?

    • ACarbohydrates
    • BLipids (Fats)
    • CVitamins
    • DNucleic acids
    Show answer & explanation

    Correct answer: B — Lipids (Fats)

    As lymph collects waste products and absorbed fats from the body tissues, lipids (fats) are significant components.

  11. Q11. Where does the flow of air change direction in the human respiratory system?

    • ABronchus
    • BTrachea
    • CBronchioles
    • DLarynx
    Show answer & explanation

    Correct answer: A — Bronchus

    Air flows from the trachea into the bronchi, which further divide into bronchioles, demonstrating a change in pathway direction as it moves deeper into the lungs.

  12. Q12. Heart failure primarily results from a failure of the heart to perform which basic function?

    • ARegulation of peripheral nerve impulses
    • BRegulation of blood pH
    • CRegulation of blood glucose
    • DRegulation of systemic blood pressure
    Show answer & explanation

    Correct answer: D — Regulation of systemic blood pressure

    Heart failure is fundamentally a failure of the myocardium (heart muscle) to pump blood effectively to meet the body's metabolic demands, which impacts systemic blood pressure regulation.

  13. Q13. The blood flow in the pulmonary circulation is responsible for which physiological process?

    • AExchange of oxygen and carbon dioxide
    • BRegulation of blood volume
    • CSystemic delivery of nutrients
    • DRegulation of blood pressure
    Show answer & explanation

    Correct answer: A — Exchange of oxygen and carbon dioxide

    The pulmonary circulation facilitates the exchange of gases (oxygenation) between blood and air in the lungs.

  14. Q14. If the heart rate of a person increases while the stroke volume remains constant, what happens to the overall cardiac output?

    • ACardiac output decreases
    • BCardiac output remains unchanged
    • CCardiac output increases
    • DCardiac output is inversely related to stroke volume.
    Show answer & explanation

    Correct answer: C — Cardiac output increases

    Since Cardiac Output (CO) = Heart Rate (HR) × Stroke Volume (SV), if HR increases and SV is constant, the total Cardiac Output will increase proportionally.

  15. Q15. The blood vessels supplying the cardiac muscle itself are primarily categorized as:

    • AArteriole
    • BArteries
    • CVeins
    • DCapillaries
    Show answer & explanation

    Correct answer: B — Arteries

    The coronary arteries supply oxygenated blood directly to the myocardium (heart muscle) via the coronary circulation.

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