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NEET Biology: Disorders of circulatory system-Angina pectoris Practice Questions

15 free multiple-choice questions on Disorders of circulatory system-Angina pectoris (Human Physiology) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. During stable angina, the chest pain is primarily caused by the imbalance between myocardial oxygen supply and demand during physical exertion. What is the main underlying structural issue causing this limitation?

    • ASudden blockage of the coronary arteries
    • BIncreased heart rate leading to systemic hypoxia
    • CAcute rupture of a thrombus
    • DFixed narrowing of coronary arteries due to atherosclerosis
    Show answer & explanation

    Correct answer: D — Fixed narrowing of coronary arteries due to atherosclerosis

    Stable angina occurs when the fixed narrowing of the coronary arteries (atherosclerosis) limits blood flow during increased myocardial oxygen demand (like during exercise).

  2. Q2. Angina Pectoris is primarily caused by what physiological event in the heart muscle?

    • ADecreased blood pressure
    • BHypertrophy of the left ventricle
    • CIschemia due to insufficient oxygen supply
    • DIncreased heart rate
    Show answer & explanation

    Correct answer: C — Ischemia due to insufficient oxygen supply

    Angina pectoris is chest pain caused by myocardial ischemia, which occurs when the heart muscle does not receive enough oxygen-rich blood (ischemia).

  3. Q3. The underlying pathological process leading to the development of coronary artery disease, which causes angina, is primarily:

    • AHypertrophy of the atrial muscle
    • BAtherosclerosis of the coronary arteries
    • CHyperplasia of the cardiac tissue
    • DInflammation of the valve leaflets
    Show answer & explanation

    Correct answer: B — Atherosclerosis of the coronary arteries

    Angina is a symptom of coronary artery disease, which is characterized by the buildup of plaque (atherosclerosis) in the coronary arteries.

  4. Q4. Which of the following conditions primarily leads to myocardial ischemia in the context of angina pectoris?

    • Aincreased myocardial oxygen demand
    • Breduced coronary blood flow
    • Cdecreased blood pressure
    • Dincreased sympathetic tone
    Show answer & explanation

    Correct answer: A — increased myocardial oxygen demand

    Angina pectoris occurs when there is an imbalance between the oxygen supply and the oxygen demand of the heart muscle. If the supply of oxygen (coronary blood flow) is insufficient to meet the increased demand, myocardial ischemia results.

  5. Q5. The pain experienced during angina is typically described as:

    • ACrushing pain in the back
    • BSharp, stabbing pain
    • CBurning sensation in the throat
    • DTightness, pressure, or squeezing sensation
    Show answer & explanation

    Correct answer: D — Tightness, pressure, or squeezing sensation

    Angina is classically described as a sensation of tightness, pressure, or squeezing in the chest, reflecting the myocardial ischemia.

  6. Q6. What is the key distinction between stable angina and unstable angina regarding the severity and predictability of the chest pain?

    • AStable angina involves inflammation, unstable angina involves thrombosis.
    • BStable angina is always caused by blockages, unstable angina by spasm.
    • CStable angina is predictable, occurring with exertion and relieved by rest, unstable angina is unpredictable and occurs at rest.
    • DStable angina occurs only during rest, unstable angina during exertion.
    Show answer & explanation

    Correct answer: C — Stable angina is predictable, occurring with exertion and relieved by rest, unstable angina is unpredictable and occurs at rest.

    Stable angina is predictable and occurs with exertion and relieves with rest. Unstable angina (or acute coronary syndrome) is unpredictable and can occur at rest.

  7. Q7. Angina is often triggered by an imbalance between:

    • ACardiac output and peripheral resistance
    • BSystolic and diastolic blood pressure
    • CBlood volume and pressure
    • DOxygen supply and oxygen demand
    Show answer & explanation

    Correct answer: D — Oxygen supply and oxygen demand

    Angina arises when the oxygen demand of the heart muscle exceeds the oxygen supply, leading to ischemia.

  8. Q8. Which layer of the heart wall is most frequently affected during a myocardial ischemia leading to angina?

    • APericardium
    • BMyocardium
    • CEndocardium
    • DEpicardium
    Show answer & explanation

    Correct answer: B — Myocardium

    The myocardium (the middle layer of the heart wall) is the tissue that requires the most oxygen, and therefore, ischemia primarily affects this layer.

  9. Q9. Atherosclerosis, the underlying cause of most coronary artery disease, involves the buildup of which substance within the arterial walls?

    • AElastin
    • BPlaque (fats and cholesterol)
    • CCollagen
    • DMyosin
    Show answer & explanation

    Correct answer: B — Plaque (fats and cholesterol)

    Atherosclerosis is the hardening and narrowing of the arteries due to the buildup of plaque, which restricts blood flow to the heart.

  10. Q10. Which vessel is primarily responsible for supplying blood to the heart muscle itself (myocardium)?

    • AAorta
    • BCoronary arteries
    • CVena Cava
    • DPulmonary artery
    Show answer & explanation

    Correct answer: B — Coronary arteries

    The coronary arteries supply oxygenated blood directly to the myocardium, which is essential for heart muscle function.

  11. Q11. The main physiological consequence of myocardial ischemia during an angina attack is:

    • AIncreased cardiac contractility
    • BDecreased blood pressure
    • CIncreased sympathetic response leading to relaxation
    • DReduced ATP production and cellular hypoxia
    Show answer & explanation

    Correct answer: D — Reduced ATP production and cellular hypoxia

    Insufficient oxygen supply (hypoxia) prevents the heart muscle cells from producing sufficient ATP, which is the basis of the pain and potential damage.

  12. Q12. The sensation of chest pain in angina is typically localized to which region?

    • AChest
    • BUpper abdomen
    • CBack
    • DLeft shoulder
    Show answer & explanation

    Correct answer: A — Chest

    Pain originating from the heart or coronary arteries is commonly perceived as a pressure or squeezing sensation localized to the chest area.

  13. Q13. Which of the following factors generally triggers the onset of angina in patients with underlying coronary artery disease?

    • Aphysical exertion
    • Bemotional stress
    • Cprolonged rest
    • Dheavy lifting
    Show answer & explanation

    Correct answer: A — physical exertion

    Physical exertion increases the heart's demand for oxygen, which the narrowed coronary arteries cannot meet, thereby causing ischemia (angina).

  14. Q14. Atherosclerosis is the underlying process responsible for the development of most coronary artery diseases. This process involves the buildup of which substance in the artery walls?

    • Acholesterol and fat
    • Bcalcium deposits
    • Ciron oxide
    • Dfibrin and platelets
    Show answer & explanation

    Correct answer: A — cholesterol and fat

    Atherosclerosis is the hardening and narrowing of the arteries due to the accumulation of plaque, primarily cholesterol and fats, within the vessel walls.

  15. Q15. Which major blood vessel is typically narrowed or blocked in cases of coronary artery disease leading to angina?

    • AAorta
    • BCarotid artery
    • CPulmonary artery
    • DCoronary arteries
    Show answer & explanation

    Correct answer: D — Coronary arteries

    Angina arises from the narrowing or blockage of the coronary arteries, which supply blood to the heart muscle.

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