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NEET Biology: Disorders related to respiration-Asthma Practice Questions

15 free multiple-choice questions on Disorders related to respiration-Asthma (Human Physiology) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. The accumulation of inflammatory cells (like eosinophils and mast cells) in the bronchial walls is characteristic of which stage of the asthma disease process?

    • AAcute phase
    • BEarly sensitization
    • CLate chronic phase
    • DReversal phase
    Show answer & explanation

    Correct answer: C — Late chronic phase

    Chronic inflammation and cellular infiltration characterize the chronic phase of asthma, leading to persistent airway remodeling.

  2. Q2. Which physiological change is a direct consequence of inflammation in the airways during asthma?

    • AIncreased lung volume
    • BDecreased airway elasticity
    • CIncreased airway hyperresponsiveness
    • DDecreased pulmonary blood flow
    Show answer & explanation

    Correct answer: C — Increased airway hyperresponsiveness

    Inflammation causes edema and smooth muscle contraction, leading to increased airway hyperresponsiveness, making the airways more sensitive to stimuli.

  3. Q3. Asthma is primarily characterized by which type of airflow limitation?

    • AIncreased static compliance
    • BDecreased elastic recoil
    • CFixed airflow limitation
    • DAir trapping
    Show answer & explanation

    Correct answer: D — Air trapping

    Asthma involves variable airflow limitation, often manifested as air trapping due to bronchoconstriction and airway narrowing, which is reversible.

  4. Q4. The characteristic sound heard during an asthma attack, caused by narrowed airways, is known as:

    • ACrackles
    • BWheezing
    • CStridor
    • DRhonchi
    Show answer & explanation

    Correct answer: B — Wheezing

    Wheezing is the high-pitched whistling sound produced when air is forced through narrowed airways, a hallmark symptom of asthma.

  5. Q5. The sound of wheezing in asthma is primarily caused by:

    • AVibrations in the chest wall
    • BVibrations in the larger bronchi
    • CNarrowing of the small airways
    • DIncreased friction in the alveoli
    Show answer & explanation

    Correct answer: C — Narrowing of the small airways

    Wheezing is the whistling sound produced by air flowing through narrowed, constricted small airways during forced expiration.

  6. Q6. Which physiological change is primarily observed in the airways following the administration of a bronchodilator medication to a patient with asthma?

    • AIncreased mucus secretion
    • BDecreased bronchial smooth muscle tone
    • CIncreased forced expiratory volume in one second (FEV1)
    • DIncreased airway inflammation
    Show answer & explanation

    Correct answer: C — Increased forced expiratory volume in one second (FEV1)

    Bronchodilators work by relaxing the smooth muscles surrounding the bronchi, which reduces airway resistance. This action directly leads to an increase in the forced expiratory volume in one second (FEV1), indicating improved airflow.

  7. Q7. Which of the following symptoms is most commonly associated with the acute phase of an asthma exacerbation?

    • ANormal chest expansion
    • BTachypnea (rapid breathing)
    • CNormal resting respiratory rate
    • DDecreased oxygen saturation
    Show answer & explanation

    Correct answer: B — Tachypnea (rapid breathing)

    Asthma causes distress and increased work of breathing, leading to tachypnea (rapid breathing) as the body attempts to compensate for the increased airway resistance and ventilation demands.

  8. Q8. The primary physiological mechanism responsible for the narrowing of the airways during an asthma attack is:

    • AInflammatory cell accumulation
    • BBronchial smooth muscle contraction
    • CIncreased airway resistance
    • DMucus hypersecretion
    Show answer & explanation

    Correct answer: B — Bronchial smooth muscle contraction

    Asthma involves inflammation leading to the contraction of the bronchial smooth muscles, which narrows the airways.

  9. Q9. Airway obstruction in asthma is fundamentally caused by an imbalance between airway smooth muscle tone and which other factor?

    • AMucus volume
    • BAirflow velocity
    • CBronchial elasticity
    • DInflammatory mediators
    Show answer & explanation

    Correct answer: D — Inflammatory mediators

    Airway obstruction results from increased muscle tone (constriction) and excessive inflammation, which is driven by inflammatory mediators.

  10. Q10. Which substance is primarily released by mast cells during an allergic reaction that contributes to airway inflammation in asthma?

    • AEpinephrine
    • BHistamine
    • CProstaglandin E2
    • DThrombin
    Show answer & explanation

    Correct answer: B — Histamine

    Histamine is a key mediator released by mast cells, which causes vasodilation and increased mucus secretion, contributing to the symptoms of asthma.

  11. Q11. Reversibility of airflow limitation in asthma is a key distinguishing feature compared to fixed obstructive diseases. This reversibility is primarily attributed to:

    • AAirway remodeling
    • BBronchodilation
    • CBronchial fibrosis
    • DAlveolar collapse
    Show answer & explanation

    Correct answer: B — Bronchodilation

    The reversibility of asthma symptoms is often due to the relaxation of the smooth muscles surrounding the airways, making the obstruction temporarily reversible upon treatment.

  12. Q12. Airway remodeling in chronic asthma typically involves the thickening of which structures?

    • AAlveolar walls
    • BPleural space
    • CLungs parenchyma
    • DCartilage and sub-epithelial tissues of the airways
    Show answer & explanation

    Correct answer: D — Cartilage and sub-epithelial tissues of the airways

    Airway remodeling in chronic asthma involves structural changes in the airway walls, including fibrosis and thickening of the cartilage and surrounding tissues, leading to fixed airflow limitation.

  13. Q13. What is the primary function of the cilia lining the respiratory tract?

    • AMucociliary clearance
    • BPhonation
    • CPulmonary circulation
    • DGas exchange
    Show answer & explanation

    Correct answer: A — Mucociliary clearance

    Cilia, along with mucus, form the mucociliary escalator, which is essential for trapping debris and moving mucus (and trapped pathogens) out of the airways.

  14. Q14. Which substance is typically overproduced in the airways during an asthma attack, leading to airway narrowing?

    • ANitric Oxide
    • BCarbon Dioxide
    • COxygen
    • DMucus
    Show answer & explanation

    Correct answer: D — Mucus

    Inflammation causes the airways to produce excess mucus, which further narrows the passage for air, contributing to symptoms.

  15. Q15. Which finding is often associated with chronic airway inflammation in asthma patients?

    • AIncreased lung compliance
    • BIncreased airway hyperresponsiveness
    • CReduced sensitivity to bronchoconstrictors
    • DDecreased airway tone
    Show answer & explanation

    Correct answer: B — Increased airway hyperresponsiveness

    Chronic inflammation leads to persistent airway sensitivity, resulting in increased airway hyperresponsiveness to various stimuli.

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