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NEET Biology: Disorders-Uraemia Practice Questions

14 free multiple-choice questions on Disorders-Uraemia (Excretory Products and their elimination) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. Which of the following substances is the primary excretory product of amino acid metabolism in humans?

    • AUric acid
    • BUrea
    • CAmmonia
    • DCreatinine
    Show answer & explanation

    Correct answer: B — Urea

    The breakdown of amino acids (deamination) produces ammonia, which is then converted into urea in the liver for excretion via the kidneys.

  2. Q2. The major site for the metabolic breakdown of amino acids, resulting in ammonia production, occurs in which organ?

    • ASpleen
    • BPancreas
    • CKidney
    • DLiver
    Show answer & explanation

    Correct answer: D — Liver

    The liver is responsible for deamination of amino acids, converting excess amino groups into ammonia, which is then transported to the kidneys for excretion.

  3. Q3. Which part of the kidney is primarily responsible for the final elimination of waste materials from the body?

    • ARenal Artery
    • BRenal Cortex
    • CRenal Pelvis
    • DRenal Medulla
    Show answer & explanation

    Correct answer: C — Renal Pelvis

    The renal pelvis collects urine from the collecting ducts and serves as the conduit for its transport away from the kidney for elimination.

  4. Q4. Uremia is a condition resulting from the accumulation of which substance in the blood due to kidney dysfunction?

    • ASodium
    • BGlucose
    • CCalcium
    • DCreatinine
    Show answer & explanation

    Correct answer: D — Creatinine

    Uremia is the symptom caused by the failure of the kidneys to excrete waste products, leading to the accumulation of substances like urea and creatinine in the blood.

  5. Q5. The filtration process in the kidney that allows for the removal of blood components and wastes occurs primarily in the:

    • ALoop of Henle
    • BGlomerulus
    • CCollecting Duct
    • DRenal Cortex
    Show answer & explanation

    Correct answer: B — Glomerulus

    The glomerulus is a network of capillaries where blood pressure drives the filtration of plasma and waste products into Bowman's capsule.

  6. Q6. In a patient suffering from kidney failure, what is the typical biochemical finding related to the excretion of urea?

    • ANormal plasma urea concentration
    • BDecreased plasma urea concentration
    • CDecreased blood urea nitrogen (BUN)
    • DIncreased plasma urea concentration
    Show answer & explanation

    Correct answer: D — Increased plasma urea concentration

    Due to impaired renal excretion, urea remains in the bloodstream, causing an elevation in plasma urea concentration.

  7. Q7. The primary function of the renal tubules in the nephron is to facilitate which process?

    • ABlood clotting
    • BReabsorption and Secretion
    • CHormone synthesis
    • DHormone secretion
    Show answer & explanation

    Correct answer: B — Reabsorption and Secretion

    The renal tubules are essential for selectively reabsorbing necessary substances (like water and glucose) and secreting unwanted substances into the filtrate before final excretion.

  8. Q8. Which of the following is a major nitrogenous waste product excreted by the kidneys?

    • ACarbon dioxide
    • BUrea
    • CLactic acid
    • DAmmonia
    Show answer & explanation

    Correct answer: B — Urea

    Urea is the principal nitrogenous waste product formed in the liver and then eliminated by the kidneys into the urine.

  9. Q9. High levels of creatinine in the blood are often used as an indicator for which condition?

    • ASevere dehydration
    • BKidney dysfunction
    • CExcessive electrolyte intake
    • DHigh protein diet
    Show answer & explanation

    Correct answer: B — Kidney dysfunction

    Creatinine is a waste product from muscle metabolism, and its accumulation in the blood indicates impaired renal function, as the kidneys are responsible for its excretion.

  10. Q10. In the context of kidney failure, an accumulation of which substance primarily leads to symptoms of uremia?

    • APotassium
    • BSodium
    • CCalcium
    • DUrea
    Show answer & explanation

    Correct answer: D — Urea

    Uremia is caused by the buildup of nitrogenous waste products, primarily urea, in the blood when the kidneys cannot excrete them effectively.

  11. Q11. Which of the following nitrogenous waste products is primarily eliminated by the kidneys through urine formation?

    • AUric Acid
    • BAmmonia
    • CCreatine
    • DCreatinine
    Show answer & explanation

    Correct answer: D — Creatinine

    Creatinine is a waste product from muscle metabolism that is filtered and excreted by the kidneys in the urine.

  12. Q12. Which of the following is a major non-nitrogenous waste product that is filtered and eliminated by the kidneys?

    • AUrea
    • BAmmonia
    • CCreatinine
    • DLactic acid
    Show answer & explanation

    Correct answer: C — Creatinine

    Creatinine is a waste product derived from muscle metabolism and is readily filtered and excreted by the kidneys.

  13. Q13. In the context of kidney failure, the buildup of excess urea in the blood is a direct manifestation of which disorder?

    • ACirrhosis
    • BAnemia
    • CUremia
    • DDiabetes
    Show answer & explanation

    Correct answer: C — Uremia

    The excessive accumulation of urea in the blood is the defining feature and manifestation of uremia, which occurs when kidney function is impaired.

  14. Q14. Which of the following excretory organs is directly responsible for regulating the balance of water and electrolytes in the body?

    • ALiver
    • BKidneys
    • CLungs
    • DHeart
    Show answer & explanation

    Correct answer: B — Kidneys

    The kidneys are the primary organs responsible for maintaining fluid and electrolyte balance by controlling water reabsorption and the excretion of waste products.

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