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NEET Biology: Disorders-Renal failure Practice Questions

13 free multiple-choice questions on Disorders-Renal failure (Excretory Products and their elimination) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. Which structure is primarily responsible for the selective reabsorption of water and solutes by the renal tubules?

    • AGlomerulus
    • BBowman's capsule
    • CRenal tubules
    • DRenal cortex
    Show answer & explanation

    Correct answer: C — Renal tubules

    The renal tubules are the site where most of the selective reabsorption of water, salts, and solutes from the filtrate back into the blood occurs, thus regulating body fluid composition.

  2. Q2. The primary role of the nephron in the excretory system is to perform which of the following processes?

    • AHormone synthesis
    • BFiltration and reabsorption of waste products
    • CProtein synthesis
    • DBlood cell production
    Show answer & explanation

    Correct answer: B — Filtration and reabsorption of waste products

    The nephron is the functional unit of the kidney, specialized for the crucial processes of filtering blood and selectively reabsorbing necessary substances while eliminating metabolic wastes.

  3. Q3. The primary excretory product of amino acid metabolism that the kidneys filter out is:

    • AGlucose
    • BLactic acid
    • CUrea
    • DAmmonia
    Show answer & explanation

    Correct answer: C — Urea

    Urea is the end product of the catabolism (breakdown) of amino acids, and the kidneys are responsible for filtering this waste product from the blood for excretion.

  4. Q4. An accumulation of certain waste products in the blood, resulting from impaired kidney function, is often associated with which clinical sign related to systemic imbalance?

    • AAcid-Base disturbance
    • BExcess electrolyte concentration
    • CIncreased clotting factors
    • DHigh hemoglobin levels
    Show answer & explanation

    Correct answer: A — Acid-Base disturbance

    Impaired renal function directly affects the body's ability to regulate the balance of acids and bases, leading to potential acid-base disturbances.

  5. Q5. The main function of the excretory system in maintaining homeostasis is to control the concentration of which substance in the blood?

    • AWater
    • BProteins
    • CGlucose
    • DFat
    Show answer & explanation

    Correct answer: A — Water

    The excretory system, primarily the kidneys, works to maintain the balance of water and electrolyte concentration in the blood, which is essential for maintaining physiological homeostasis.

  6. Q6. Which of the following is a key indicator used to assess the overall functional capacity and filtration rate of the kidneys?

    • ASerum Protein level
    • BBlood Urea Nitrogen (BUN)
    • CBlood Glucose level
    • DSerum Cholesterol level
    Show answer & explanation

    Correct answer: B — Blood Urea Nitrogen (BUN)

    Blood Urea Nitrogen (BUN) is a commonly measured indicator reflecting the kidney's efficiency in filtering waste products from the blood.

  7. Q7. Which part of the nephron is primarily responsible for the selective reabsorption of water and solutes back into the blood?

    • AProximal convoluted tubule
    • BDistal convoluted tubule
    • CGlomerulus
    • DBowman's capsule
    Show answer & explanation

    Correct answer: A — Proximal convoluted tubule

    The Proximal convoluted tubule (PCT) is the site where the majority (about 65-70%) of water and solutes are reabsorbed from the filtrate back into the blood, which is critical for regulating body fluid balance.

  8. Q8. Renal failure primarily impairs the kidney's ability to maintain homeostasis. Which function is most directly affected by the inability to regulate water balance in the body?

    • ABlood pH
    • BBlood clotting mechanism
    • COsmotic pressure of extracellular fluid
    • DBlood glucose levels
    Show answer & explanation

    Correct answer: C — Osmotic pressure of extracellular fluid

    The kidneys are crucial for regulating water reabsorption, which directly controls the osmotic pressure of the extracellular fluid.

  9. Q9. Which blood component is the primary medium for transporting metabolic wastes, such as urea, to the excretory organs?

    • APlasma
    • BRed Blood Cells (RBCs)
    • CWhite Blood Cells (WBCs)
    • DPlatelets
    Show answer & explanation

    Correct answer: A — Plasma

    Blood plasma is the extracellular fluid that carries dissolved substances, including nitrogenous wastes (like urea) formed by metabolism, to the excretory organs (kidneys) for filtration and elimination.

  10. Q10. In cases of renal failure, the inability to excrete metabolic waste products leads to the accumulation of which of the following substances in the blood?

    • AUrea and Creatinine
    • BGlucose
    • CLipids
    • DAmino acids
    Show answer & explanation

    Correct answer: A — Urea and Creatinine

    When kidney function is impaired, the excretion of nitrogenous wastes like urea and creatinine is reduced, leading to their accumulation in the blood, a hallmark of renal failure.

  11. Q11. If the Glomerular Filtration Rate (GFR) is significantly reduced due to renal failure, what is the immediate consequence concerning waste removal?

    • AIncreased secretion of hormones
    • BEnhanced filtration pressure
    • CIncreased reabsorption of glucose
    • DReduced clearance rate of waste products
    Show answer & explanation

    Correct answer: D — Reduced clearance rate of waste products

    A reduced GFR means that the rate at which blood is filtered and subsequently waste is cleared from the blood is diminished.

  12. Q12. Which hormone plays a crucial role in regulating blood volume and pressure, which is significantly affected by impaired renal function?

    • AThyroxine
    • BAldosterone
    • CGrowth Hormone
    • DInsulin
    Show answer & explanation

    Correct answer: B — Aldosterone

    Aldosterone, secreted by the adrenal glands under the influence of the renin-angiotensin system, works with the kidneys to regulate sodium and water reabsorption, directly impacting blood volume and pressure.

  13. Q13. Which component of the blood is primarily filtered by the glomerulus during blood purification process?

    • APlasma
    • BRed Blood Cells
    • CPlatelets
    • DWhite Blood Cells
    Show answer & explanation

    Correct answer: A — Plasma

    The glomerulus is a network of capillaries responsible for filtering blood, which is primarily plasma.

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