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NEET Biology: Human endocrine system-Thyroid Practice Questions

15 free multiple-choice questions on Human endocrine system-Thyroid (Chemical Coordination and Regulation) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. Thyroid hormones primarily regulate which of the following bodily processes?

    • AReflex actions and heart rate
    • BBlood clotting and vasoconstriction
    • CLipolysis and blood sugar regulation
    • DProtein synthesis and tissue growth
    Show answer & explanation

    Correct answer: D — Protein synthesis and tissue growth

    Thyroid hormones are crucial regulators of the basal metabolic rate, affecting the rate of cellular metabolism, protein synthesis, and growth processes.

  2. Q2. The primary function of thyroid hormones in the body is to regulate:

    • ABlood sugar level
    • BBlood pressure
    • CElectrolyte balance
    • DBasal metabolic rate (BMR)
    Show answer & explanation

    Correct answer: D — Basal metabolic rate (BMR)

    Thyroid hormones primarily regulate the basal metabolic rate (BMR) of the body tissues, thereby controlling the rate of cellular metabolism.

  3. Q3. Which pituitary hormone plays a key role in regulating the activity of the thyroid gland?

    • AAdrenocorticotropic hormone (ACTH)
    • BGrowth Hormone (GH)
    • CProlactin
    • DThyroid-stimulating hormone (TSH)
    Show answer & explanation

    Correct answer: D — Thyroid-stimulating hormone (TSH)

    Thyroid-stimulating hormone (TSH), secreted by the pituitary gland, acts as the primary regulator, stimulating the thyroid gland to release T4 and T3.

  4. Q4. The cells of the thyroid gland that produce calcitonin are located in which part of the gland?

    • AFollicular cells
    • BParafollicular cells
    • CEndocrine cells
    • DConnective tissue
    Show answer & explanation

    Correct answer: B — Parafollicular cells

    The parafollicular cells (C cells) are found between the thyroid follicles and secrete the hormone calcitonin.

  5. Q5. The negative feedback mechanism in the thyroid axis ensures proper regulation by:

    • ADirect inhibition of the hypothalamus
    • BDecreased TSH activity when T4/T3 levels are high
    • CIncreased iodine uptake by the gland
    • DIncreased TSH activity when T4 levels are low
    Show answer & explanation

    Correct answer: B — Decreased TSH activity when T4/T3 levels are high

    When levels of T4 and T3 in the blood are adequate, they feed back to the pituitary and hypothalamus, inhibiting the release of TSH and TRH, thereby maintaining homeostasis.

  6. Q6. Which hormone is secreted by the anterior pituitary gland that stimulates the thyroid gland to produce thyroid hormones?

    • ACalcitonin
    • BAdrenocorticotropic hormone (ACTH)
    • CGrowth Hormone
    • DThyroid-stimulating hormone (TSH)
    Show answer & explanation

    Correct answer: D — Thyroid-stimulating hormone (TSH)

    Thyroid-stimulating hormone (TSH), released from the anterior pituitary, acts as the trophic hormone to stimulate the thyroid gland to synthesize T3 and T4.

  7. Q7. The main role of thyroglobulin in the synthesis pathway of thyroid hormones is to act as a precursor for which process?

    • AStoring iodine reserves
    • BRegulating TSH secretion
    • CTransporting iodine into the cell
    • DServing as the substrate for hormone formation
    Show answer & explanation

    Correct answer: D — Serving as the substrate for hormone formation

    Thyroglobulin is a large glycoprotein that acts as the substrate upon which iodine is attached and subsequently oxidized to form T3 and T4.

  8. Q8. The main role of the thyroid hormones (T3 and T4) in the body is primarily to regulate which process?

    • AProtein synthesis
    • BBasal metabolic rate (BMR)
    • CNerve impulse transmission
    • DBlood clotting
    Show answer & explanation

    Correct answer: B — Basal metabolic rate (BMR)

    Thyroid hormones primarily control the rate of cellular metabolism and thus regulate the basal metabolic rate (BMR) of the body.

  9. Q9. Which element is essential for the synthesis of thyroid hormones (T3 and T4) in the thyroid gland?

    • ACalcium
    • BIron
    • CSodium
    • DIodine
    Show answer & explanation

    Correct answer: D — Iodine

    Iodine is an essential mineral required for the synthesis of thyroid hormones by the thyroid gland.

  10. Q10. Which tissue is responsible for producing and secreting the thyroid hormones?

    • APancreas
    • BThyroid gland
    • CAdrenal cortex
    • DPituitary gland
    Show answer & explanation

    Correct answer: B — Thyroid gland

    The thyroid gland is the primary endocrine gland responsible for synthesizing and secreting thyroid hormones (T3 and T4).

  11. Q11. A deficiency of thyroid hormones typically leads to which condition?

    • AHypocalcemia
    • BHyperthyroidism
    • CHyperglycemia
    • DHypothyroidism
    Show answer & explanation

    Correct answer: D — Hypothyroidism

    A deficiency of thyroid hormones results in hypothyroidism, which slows down the body's metabolism.

  12. Q12. Which of the following is the main active form of thyroid hormone?

    • AThyroxine (T4)
    • BCalcitonin
    • CTriiodothyronine (T3)
    • DParathyroid hormone
    Show answer & explanation

    Correct answer: C — Triiodothyronine (T3)

    Triiodothyronine (T3) is the biologically active form of the thyroid hormone; T4 is the main hormone secreted by the gland, which is converted into T3 in peripheral tissues.

  13. Q13. What is the primary function of the thyroid gland in relation to metabolism?

    • AControlling reproductive cycle
    • BControlling blood glucose levels
    • CControlling blood pressure
    • DControlling the basal metabolic rate
    Show answer & explanation

    Correct answer: D — Controlling the basal metabolic rate

    Thyroid hormones directly influence the metabolic rate of all body cells, thereby controlling the overall basal metabolic rate of the organism.

  14. Q14. Which is the main site where thyroid hormones exert their effects on the body cells?

    • ABone marrow
    • BTarget tissues throughout the body
    • CAdrenal cortex
    • DLiver only
    Show answer & explanation

    Correct answer: B — Target tissues throughout the body

    Thyroid hormones regulate the metabolism and functions in nearly all body tissues, affecting energy expenditure and growth processes.

  15. Q15. Where is the thyroid gland anatomically located?

    • AAbdominal cavity
    • BAbdomen
    • CNeck
    • DChest
    Show answer & explanation

    Correct answer: C — Neck

    The thyroid gland is situated in the anterior part of the neck, just below the larynx.

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