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NEET Biology: Disorders of muscular and skeletal system-Arthritis Practice Questions

15 free multiple-choice questions on Disorders of muscular and skeletal system-Arthritis (Locomotion and Movement) for NEET Biology, each with the correct answer and a step-by-step explanation. Attempt a question, then reveal the solution to check your reasoning.

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  1. Q1. Which of the following is the primary cause of gout, an inflammatory arthritis characterized by the deposition of uric acid crystals in the joints?

    • ADegeneration of cartilage due to mechanical stress
    • BDeposition of monosodium urate crystals
    • CAutoimmune response against joint lining
    • DChronic inflammation due to systemic infection
    Show answer & explanation

    Correct answer: B — Deposition of monosodium urate crystals

    Gout is a form of inflammatory arthritis caused by the deposition of monosodium urate crystals in the joints, which leads to intense pain and inflammation.

  2. Q2. Which term best describes the characteristic pattern of joint involvement seen in many forms of arthritis?

    • ABilateral
    • BUnilateral
    • CSymmetrical
    • DAsymmetrical
    Show answer & explanation

    Correct answer: C — Symmetrical

    Many forms of arthritis, especially inflammatory types like RA, often present with symmetrical joint involvement, affecting similar joints on both sides of the body.

  3. Q3. Which component provides smooth, friction-reducing movement between bones in a synovial joint?

    • ALigaments
    • BFibrous capsule
    • CSynovial fluid
    • DArticular cartilage
    Show answer & explanation

    Correct answer: D — Articular cartilage

    Articular cartilage is the smooth layer of hyaline cartilage covering the ends of bones in a joint, which reduces friction during movement.

  4. Q4. Osteoarthritis primarily involves the degeneration of which specific tissue in the joint?

    • ASynovial membrane
    • BBone marrow
    • CLigaments
    • DArticular cartilage
    Show answer & explanation

    Correct answer: D — Articular cartilage

    Osteoarthritis is characterized by the progressive breakdown and degeneration of the articular cartilage.

  5. Q5. Rheumatoid Arthritis is an example of which type of arthritis?

    • AInfectious Arthritis
    • BInflammatory Arthritis
    • CDegenerative Arthritis
    • DCrystal-induced Arthritis
    Show answer & explanation

    Correct answer: B — Inflammatory Arthritis

    Rheumatoid Arthritis is an inflammatory form of arthritis, meaning it involves inflammation of the lining of the joints.

  6. Q6. Which of the following is the most common form of arthritis, primarily affecting the aging population and characterized by degenerative changes in the cartilage of weight-bearing joints?

    • ARheumatoid Arthritis
    • BGout
    • COsteoarthritis
    • DAnkylosing Spondylitis
    Show answer & explanation

    Correct answer: C — Osteoarthritis

    Osteoarthritis (OA) is the most common form of arthritis, characterized by the progressive breakdown and degeneration of articular cartilage, particularly in weight-bearing joints.

  7. Q7. Gout is a type of arthritis caused by the accumulation of which substance in the joints?

    • ACalcium salts
    • BUric acid
    • CVitamin D
    • DIron
    Show answer & explanation

    Correct answer: B — Uric acid

    Gout is caused by the deposition of uric acid crystals in the joints, leading to intense pain and swelling.

  8. Q8. The primary cause of inflammation in Rheumatoid Arthritis is related to which type of immune cell activity?

    • AMacrophages
    • BMast cells
    • CT-lymphocytes
    • DNeutrophils
    Show answer & explanation

    Correct answer: C — T-lymphocytes

    Rheumatoid arthritis is an autoimmune disease primarily driven by an overactive immune response involving T-lymphocytes attacking the joint lining.

  9. Q9. Which term is used to describe inflammation of the joints in the body?

    • ASpondylosis
    • BArthritis
    • COsteoporosis
    • DMuscular Dystrophy
    Show answer & explanation

    Correct answer: B — Arthritis

    Arthritis is the general term used to describe pain, stiffness, and inflammation of the joints.

  10. Q10. Rheumatoid arthritis is classified as which type of arthritis?

    • ADegenerative arthritis
    • BInfectious arthritis
    • CMetabolic arthritis
    • DInflammatory arthritis
    Show answer & explanation

    Correct answer: D — Inflammatory arthritis

    Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease that primarily affects the joints, classifying it as an inflammatory arthritis.

  11. Q11. Which fluid is found in the synovial joints and provides lubrication and nutrition to the cartilage?

    • ASynovial fluid
    • BCerebrospinal fluid
    • CBlood plasma
    • DInterstitial fluid
    Show answer & explanation

    Correct answer: A — Synovial fluid

    Synovial fluid is the specialized fluid found in the cavities of the synovial joints that reduces friction and nourishes the cartilage.

  12. Q12. Which type of joint is most commonly affected by degenerative changes leading to Osteoarthritis?

    • AHinge joints
    • BSynovial joints
    • CBall-and-socket joints
    • DPivot joints
    Show answer & explanation

    Correct answer: A — Hinge joints

    Osteoarthritis primarily affects joints where the articular cartilage wears down, which is most prominent in hinge joints (like the knee and hip) and interphalangeal joints.

  13. Q13. Which condition involves the excessive accumulation of uric acid crystals in the joints, leading to painful inflammation?

    • AGout
    • BAnkylosing Spondylitis
    • CRheumatoid Arthritis
    • DOsteoarthritis
    Show answer & explanation

    Correct answer: A — Gout

    Gout is a form of arthritis caused by the deposition of uric acid crystals in the joints.

  14. Q14. Gout is a form of inflammatory arthritis caused by the deposition of which specific substance in the joint space?

    • AUric acid crystals
    • BHyaluronic acid
    • CCalcium phosphate
    • DCollagen
    Show answer & explanation

    Correct answer: A — Uric acid crystals

    Gout is caused by the accumulation of monosodium urate crystals in the joints, leading to intense inflammation and pain.

  15. Q15. Which of the following joints is most commonly affected by severe degenerative changes leading to Osteoarthritis?

    • AFinger joints
    • BHip and knee joints
    • CWrist joints
    • DFacial joints
    Show answer & explanation

    Correct answer: B — Hip and knee joints

    The hip and knee joints are major weight-bearing joints and are highly susceptible to degenerative changes seen in Osteoarthritis.

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